TB-500

Price range: $55.00 through $95.00

TB-500 is a synthetic version of Thymosin Beta-4, a naturally occurring 43-amino acid peptide found in high concentrations in blood platelets, wound fluid, and other tissues. Thymosin Beta-4 was originally isolated from thymus extracts in the 1960s and has since been identified as a major actin-sequestering protein with significant roles in cell migration, differentiation, and tissue repair. TB-500 represents a truncated, active region of the full Thymosin Beta-4 molecule, making it more practical for research applications while retaining the key biological activity associated with the parent molecule.

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Description

Product Description

TB-500 (Thymosin Beta-4 Fragment) is a synthetic analog of the naturally occurring 43-amino acid peptide Thymosin Beta-4 (Tβ4), which plays a critical role in cell migration, proliferation, and differentiation. TB-500 represents the active region responsible for actin sequestration and tissue repair signaling.

Molecular Profile:

  • Molecular Formula: C₂₁₂H₃₅₀N₅₆O₇₈S
  • Molecular Weight: 4,963 g/mol
  • Active Sequence: LKKTETQ (amino acids 17-23 of Tβ4)
  • CAS Number: 77591-33-4

Research Applications:

  • Actin regulation and cellular migration studies
  • Wound healing and tissue regeneration mechanisms
  • Cardiac repair and cardioprotective research
  • Anti-inflammatory pathway investigation
  • Hair follicle stem cell activation studies
  • Dermal and musculoskeletal repair models

Quality Standards:

  • Purity: ≥99% verified by HPLC
  • Third-party tested with COA included
  • Lyophilized powder form

Storage & Handling:

  • Store at -20°C (lyophilized)
  • Reconstitute with bacteriostatic water
  • Reconstituted: stable 30 days at 2-8°C

FOR RESEARCH USE ONLY. Not for human consumption.

Additional information
Mg

5mg

,

10mg

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